Library resource guides: Conceptual basis of pain medicine: Management of pain

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Articles and publications

Wong SSC, Wang F, Chan TCW, Cheung CW. The analgesic effect of total intravenous anaesthesia with propofol versus inhalational anaesthesia for acute postoperative pain after hepatectomy: a randomized controlled trial. BMC Anesthesiol. 2023;23(1):112. Postoperative pain control can be challenging in patients undergoing hepatectomy. A previous retrospective study on hepatobiliary/ pancreatic surgeries showed better postoperative pain control in patients who received propofol TIVA. The aim of this study was to determine the analgesic effect of propofol TIVA for hepatectomy.
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Keywords: Adverse effects; Hepatectomy; Morphine consumption; Pain scores; Propofol TIVA.
Nicholas MK, Blyth FM. Are self-management strategies effective in chronic pain treatment?. Pain Manag. 2016;6(1):75-88. [REQUEST VIA LIBRARY] Keywords: chronic pain; cognitive–behavioral therapy; disability; pain management; self-management; strategies.
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Abstract
It has long been recognized that in the management of chronic illnesses generally, medical care alone is unlikely to be sufficient without the active contribution of the patient. This perspective has also been enunciated in numerous guidelines for the management of chronic pain. However, in the case of chronic pain at least, the nature and role of self-management have been poorly defined and, as a result, poorly understood and researched. This review considers the nature of self-management strategies for chronic pain, evidence of their effectiveness and ways in which self-management can be facilitated for those in chronic pain. A research and training agenda is proposed for where this work could go next.
Turk DC, Wilson HD, Cahana A. Treatment of chronic non-cancer pain. Lancet. 2011;377(9784):2226-2235.
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Abstract
Chronic pain is a pervasive problem that affects the patient, their significant others, and society in many ways. The past decade has seen advances in our understanding of the mechanisms underlying pain and in the availability of technically advanced diagnostic procedures; however, the most notable therapeutic changes have not been the development of novel evidenced-based methods, but rather changing trends in applications and practices within the available clinical armamentarium. We provide a general overview of empirical evidence for the most commonly used interventions in the management of chronic non-cancer pain, including pharmacological, interventional, physical, psychological, rehabilitative, and alternative modalities. Overall, currently available treatments provide modest improvements in pain and minimum improvements in physical and emotional functioning. The quality of evidence is mediocre and has not improved substantially during the past decade. There is a crucial need for assessment of combination treatments, identification of indicators of treatment response, and assessment of the benefit of matching of treatments to patient characteristics.
Cregg R, Russo G, Gubbay A, Branford R, Sato H. Pharmacogenetics of analgesic drugs. Br J Pain. 2013;7(4):189-208. Keywords: Pharmacogenetics; analgesics; genetic association studies; genetic screening; inter-individual variability; metabolism; pain; pain perception; pharmacodynamics; pharmacogenomics; pharmacokinetics; phenotype; polymorphism; single-nucleotide polymorphism.
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Abstract
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. • While pharmacokinetic properties of drugs, metabolism in particular, have been scrutinised by genotype-phenotype correlation studies, the clinical significance of inherited variants in genes governing pharmacodynamics of analgesics remains largely unexplored (apart from the µ-opioid receptor). • Lack of replication of the findings from one study to another makes meaningful personalised analgesic regime still a distant future. • This narrative review will focus on findings related to pharmacogenetics of commonly used analgesic medications and highlight authors' views on future clinical implications of pharmacogenetics in the context of pharmacological treatment of chronic pain.

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ANZCA & FPM resources

PS01(PM) (Appendix) 2021: Opioid Dose Equivalence Calculation Table
Faculty of Pain Medicine. FPM opioid dose equivalence chart [Internet].

Acute Pain Management: A Practical Guide, 5e by Pamela E. Macintyre; Stephan A. Schug With a focus on practical acute pain management in adults in the hospital setting, this book provides health professionals with simple and practical information to help them manage patients with acute pain safely and effectively. * Combines evidence-based information with practical guidelines and protocols * Covers the pharmacology of opioids, local anesthetics, and nonopioid and adjuvant analgesic agents * Discusses management of acute pain in both surgical and nonsurgical acute pain settings including in patients with spinal cord or burns injuries and selected medical illnesses.
Call Number: 616.0472 MAC
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ISBN: 9780429295058

Publication Date: 2021-06-21
Acute Pain Management: Scientific Evidence, 5e by Schug, Palmer, Scott; Halliwell, Alcock & Mott [eds] Acute Pain Management: Scientific Evidence covers a wide range of clinical topics, combining a review of the best available evidence for acute pain management with current clinical and expert practice.
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Publication Date: 2020
Note: This e-book is downloadable as a PDF.
Pharmacology of Pain by Pierre Beaulieu; David Lussier; Frank Porreca; Anthony Dickenson [eds] Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain.
Call Number: 615.783 PHA
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ISBN: 9780931092787

Publication Date: 2010-01-01
Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care by Alan David Kaye; Adam M. Kaye; Richard D. Urman [eds] In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships.
ISBN: 9781461489474

Publication Date: 2014-11-21