U2M10: Antibiotic Stewardship
Discusses the role of antimicrobial prophylaxis and stewardship in the perioperative setting
These resources appear throughout the module to support learning outcomes.
Recommended texts
Antimicrobial Stewardship in Australian Health Care
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Antimicrobial Stewardship in Australian Health Care (the AMS Book), initially published in 2018, continues to be updated and enhanced with additional evidence, information, and topic areas to inform Antimicrobial Stewardship (AMS) strategies, interventions, and implementation across a range of healthcare settings. As new resources become available, these will be added as hyperlinks to the AMS Book.
Antimicrobial Stewardship: Systems and Processes for Effective Antimicrobial Medicine Use
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This guideline covers the effective use of antimicrobials (including antibiotics) in children, young people and adults. It aims to change prescribing practice to help slow the emergence of antimicrobial resistance and ensure that antimicrobials remain an effective treatment for infection.
Global Guidelines for the Prevention of Surgical Site Infection, 2e
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The first ever Global guidelines for the prevention of surgical site infection (SSI) were published on 3 November 2016, then updated in some parts and published in a new edition in December 2018. They include a list of 29 concrete recommendations on 23 topics for the prevention of SSI in the pre-, intra and postoperative periods, which are based on 28 systematic reviews of the evidence. For the 2018 update, the membership of the guidelines development group (GDG) was broadened to include an additional eight anaesthesiology experts.
The 2018 edition of the guidelines includes the revision of the recommendation regarding the use of 80% fraction of inspired oxygen (high FiO2) in surgical patients under general anaesthesia with tracheal intubation and the update of the section on implementation. Between 2017 and 2018, WHO re-assessed the evidence on the use of high FiO2 by updating the systematic review related to the effectiveness of this intervention to reduce SSI and commissioning an independent systematic review on adverse events potentially associated with it. Based on the updated evidence, the GDG decided to revise the strength of the recommendation from strong to conditional.
These updated WHO guidelines are valid for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.
National Safety and Quality Health Service Standards, 2e
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The National Safety and Quality Health Service (NSQHS) Standards were developed by the Australian Commission on Safety and Quality in Health Care (the Commission) in collaboration with the Australian Government, states and territories, the private sector, clinical experts, patients and carers. The primary aims of the NSQHS Standards are to protect the public from harm and to improve the quality of health service provision. They provide a quality assurance mechanism that tests whether relevant systems are in place to ensure that expected standards of safety and quality are met. There are eight NSQHS Standards, which cover high-prevalence adverse events, healthcareassociated infections, medication safety, comprehensive care, clinical communication, the prevention and management of pressure injuries, the prevention of falls, and responding to clinical deterioration. Importantly, these NSQHS Standards have provided a nationally consistent statement about the standard of care consumers can expect from their health service organisations.
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